Pluto Bioinformatics

GSE112201: RNA Misplicing in Fuchs Endothelial Corneal Dystrophy II

Bulk RNA sequencing

RNA-Seq splicing data from the corneal endothelia of FECD patients and controls reveal hundreds of differential alternative splicing events. These include events previously characterized in the context of myotonic dystrophy type 1 and epithelial-to-mesenchymal transition, as well as splicing changes in genes related to proposed mechanisms of FECDpathogenesis SOURCE: Michael,P,Fautsch (Fautsch.Michael@mayo.edu) - Mayo Clinic