We identify regulatory mechanisms that influence inflammation and metabolism during metabolic disease development. In addition to the other data represented in our paper, we performed RNA-seq to demonstrate a role for miR-146a, an anti-inflammatory miRNA, in regulating both inflammation and cellular metabolism during obesity. SOURCE: Morgan Nelson (morgan.nelson@path.utah.edu) - Ryan O'Connell University of Utah

Pluto Bioinformatics

GSE119703: Sequencing of F4/40+ CD11b+ macrophages from adipose tissue of miR-146a WT or deficient mice on high fat or normal chow diet