Pluto Bioinformatics

GSE117329: Transcriptomic analysis of primary human hepatic stellate cells undergoing TGFb mediated activation and JQ1 mediated attenuation of activation

Bulk RNA sequencing

Comparison of longitudinal transcriptomic profiles of activated human primary hepatic stellate cells to activated human primary hepatic stellate cells that are treated with anti-fibrotic inhibitor reveals inflammatory signaling as a key pathway that is modulated during pro-fibrotic activation and repressed during attenuation of fibrotic response. SOURCE: Jessica Min-debartolo (Jessica.Min-debartolo@pfizer.com) - Pfizer Inc