Pluto Bioinformatics

GSE55790: Next Generation Sequencing of Wild-Type FVB/NJ Mouse Cardiac Polyadenylated RNA

Bulk RNA sequencing

Purpose: Next-generation sequencing (NGS) provides for quantitation of RNA abundances and comparison of RNA abundances within tissues and cells in a manner not possible with previous microarray technologies.; We have made widespread use of Illumina sequencing technologies for RNA quantitation in several publications involving mouse hearts, dating from 2010, and wish to share both high-quality raw sequencing data and data processed to quantitate mRNA abundances from wild-type mice, male and female, at a variety of ages.; These data will provide a resource for investigators using microarrays to understand the concentration of transcripts of interest relative to other cardiac RNAs, and will permit deeper interpretation of previous microarray studies. SOURCE: Scot,J,Matkovich (smatkovich@gmail.com) - Washington University School of Medicine

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