Pluto Bioinformatics

GSE124817: Glucocorticoids Promote Breast Cancer Metastasis

Bulk RNA sequencing

Next Generation Sequencing was applied to investigate the heterogeneity between tumors and distant metastases in different models of Breast Cancer cell lines and primary-derived xenografts. Global transcriptional profiling of the primary tumor and matched distant metastases (lung, liver, spleen) as well as circulating tumor cells (CTCs) allowed to identify glucocorticoid signalling as a mediator of metastasis. SOURCE: Mohamed Bentires-Alj ( - THMR University Hospital Basel

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