Pluto Bioinformatics

GSE114015: RNA sequencing data of Wild Type and Fmr1 KO hippocampal neuron

Bulk RNA sequencing

Fragile X syndrome (FXS), caused by mutations in fragile X mental retardation 1 gene (FMR1), is a prevailing genetic disorder of intellectual disability and autism. Analysis of transcriptome outcome (differentially expressed genes between WT and Fmr1 KO hippocampal neuron) associated with FXS reveal promising value of gene signature-based computation in repurposing drugs for potential practical treatment. SOURCE: Zhuang Miao (miaozhua@msu.edu) - Hongbing Wang Michigan State University