Enhancing brown fat activity and promoting white fat browning are attractive therapeutic strategies for obesity and its associated metabolic disorders. To provide a comprehensive picture of the regulatory network in these processes, we conducted a series of transcriptome studies by RNA-seq and quantified the mRNA and lncRNA changes during white fat browning induced by chronic cold exposure, beta-adrenergic agonist and intensive exercises, brown fat activation by acute cold exposure and inactivation by thermoneutrality. SOURCE: Xiaoran Chai (chaix@gis.a-star.edu.sg) -  Genome Institute of Singapore

Pluto Bioinformatics

GSE86338: RNA profiling to describe the transcriptional change during white fat browning, brown fat activity and inactivation