Pluto Bioinformatics

GSE133928: A topological atlas reveals layers of genome reorganization in colorectal cancer

Bulk RNA sequencing

To understand how nuclear architecture is altered in cancer, we profiled genome topology along with DNA methylation, chromatin modifications and the DNA binding factors CTCF in primary colon tumors, normal colon and colon cancer cell lines. SOURCE: Alejandro Reyes (ALEJANDRO_REYES@dfci.harvard.edu) - DANA-FARBER CANCER INSTITUTE INC