Pluto Bioinformatics

GSE113524: A Paradigm Shift in Alzheimer's Disease Precipitation, Progression and Potential Prevention

Bulk RNA sequencing

De novo mutated ADNP is a most prevalent gene driving syndromic autism with intellectual disability. Using droplet digital PCR and RNA sequencing we identified somatic mutations in ADNP and in other genes in the olfactory bulb and hipocampi of Alzheimer's disease (AD) patients. SOURCE: Illana Gozes (igozes@tauex.tau.ac.il) - Gozes lab Tel-Aviv University