Pluto Bioinformatics

GSE44359: High resolution transcriptome-wide RNA cytosine methylome of Mouse Embryonic Fibroblasts

Bulk RNA sequencing

We report high resolution transcriptome-wide RNA cytosine methylome of Mouse Embryonic Fibroblasts (MEFs) revealed by an optimized new RNA bisulfite sequencing approach. Comparison of RNA methylation profile from wild-type and Dnmt2 -/- MEFs shows that only C38 in three tRNAs (tRNA-Asp, Gly and Val) is the target of Dnmt2 in MEFs at normal conditions. SOURCE: Vahid KhoddamiBradley R Cairns Huntsman Cancer Institute-University of Utah