Pluto Bioinformatics

GSE131263: Next Generation Sequencing Analysis of Prenatal Chlorpyrifos Exposure embryonic kidneys

Bulk RNA sequencing

Purpose: In order to study signaling pathway changes of prenatal chlorpyrifos exposure embryonic kidney development; Methods: By using RNA-seq, we studied the transcriptome of E12.5, E14.5, E16.5 and E18.5 prenatal chlorpyrifos exposure embryonic kidneys and DMSO exposure (control) embryonic kidneys; Results: We show that Notch signaling pathway and aquaporin family had high expression in chlorpyrifos exposure E18.5 kidney. The nephron progenitor markers had low expression in chlorpyrifos exposure embryonic kidneys SOURCE: Bingjue Li (libingjue@foxmail.com) - Zhejiang University