Pluto Bioinformatics

GSE152005: BET Bromodomain Proteins Regulate Transcriptional Reprogramming in Genetic Dilated Cardiomyopathy

Bulk RNA sequencing

In a model of chronic heart failure, BET bromodomain inhibition delayed cardiac remodeling and fibrosis by halting pathologic inflammatory gene networks in an NFkB-dependent manner. SOURCE: Andrew Antolic (Andrew.antolic@emory.edu) - Burke Emory University