Pluto Bioinformatics

GSE77541: Genome-wide expression profile in Fh1-competent vs Fh1-deficient mouse kidney cells

Bulk RNA sequencing

Comparison of the transcriptome of immortalised mouse kidney epithelial cells either wt for Fh1 or Fh1-deficient. The cells were isolated from kidneys of P5 mouse(see Frezza et al, Nature 2011). Briefly, Fh1_fl (flox) are wt for Fh1 (floxed cassette not excised), clone 1 and clone 19 are two different Fh1-deificent clones (floxed cassette excised) and Rec are clone 19 with reconstituted Fh1 expression from exogenous plasmid. SOURCE: Chandra Chilamakuri (datasubmissions@cruk.cam.ac.uk) - Cancer Research UK Cambridge Institute