Pluto Bioinformatics

GSE103471: Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma

Bulk RNA sequencing

We isolated RNAs from hematopoietic stem and progenitor cells (HSPCs). We compared two groups of mice: Cicflox/flox (control) and UBC-cre/ERT2; Cicflox/flox (knockout), two weeks post tamoxifen treatment. Following RNA isolation, RNAseq was performed and gene expression profiles were compared between controls and conditional knockouts. SOURCE: Qiumin Tan (qtan@bcm.edu) - Huda Zoghbi Baylor College of Medicine

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