Pluto Bioinformatics

GSE103400: RNA sequncing of HCN3+ urinary tract pacemaker cells

Bulk RNA sequencing

Purpose: to analyze the mRNA content of highly purified HCN3+ urinary tract pacemaker cells compared to HCN3- neighboring cells; Methods: we sorted HCN3+ and HCN3- cells from E18.5 WT embryos and analyzed their content using RNA-seq; Results: Identified differentially expressed transcripts in HCN3+ cells compared to HCN3- cells; Conclusions: our study presents the first whole transcriptome analysis of HCN3+ urinary tract pacemaker cells that would provide a basis for the charactarization of the development and function of those cells SOURCE: Norman Rosenblum (norman.rosenblum@sickkids.ca) - Hospital for sick children

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