We profiled retinal progenitor cells by integrating next generation sequencing methods and interrogating changes in chromatin accessibility at embryonic and post-natal murine stages. We identified putative factors involved in the developmental progression of the  retinal progenitors epigenome and we report Lhx2 role in the regulation of chromatin accessibility by coordinated action of developmentally regulated pioneer factors SOURCE: Seth Blackshaw (sblack@jhmi.edu) -  Johns Hopkins University School of Medicine

Pluto Bioinformatics

GSE99818: Lhx2 controls changes in chromatin accessibility in retinal progenitor cells during developmental competence transitions.