Pluto Bioinformatics

GSE102335: Microglia innatly develop within cerebral organoids

Bulk RNA sequencing

Here we report that human organoid-grown microglia have transcriptional identity similar to that of human ex vivo adult primary microglia. By performing RNAseq on total coding RNA we show that crucial genes necessary for microglia development and identity are expressed at similar levels between the 2 groups. SOURCE: Ronald,Jeroen,Pasterkamp (r.j.pasterkamp@umcutrecht.nl) - Pasterkamplab UMC Utrecht