Pluto Bioinformatics

GSE145308: Pooled CRISPR screens in human intestinal organoids [RNA-seq]

Bulk RNA sequencing

We performed CRISPR screens on both a sub-library and a genome-wide scale in human intestinal organoids to discover cancer driver genes. We investigated the Wnt and the TGFB pathway and used both WT, APC-mutant and APC-TP53-mutant organoids. SOURCE: giancarlo russo (giancarlo.russo@fgcz.ethz.ch) - ETH/University of Zurich