Pluto Bioinformatics

GSE102768: Effect of CBL0137 on gene expression in mouse cells and tissues

Bulk RNA sequencing

We analyzed changes in abundance of RNAs in mouse embryonic fibroblasts (MEF) from wild type and p53 knockout mice and in lungs of NIH Swiss mice upon treatment with 1microM (cells) or 60mg/kg IV (mice) of curaxin CBL0137 for 24 hours. CBL0137 is chromatin destabilizing agent. SOURCE: Irwin Gelman Roswell Park Cancer Insitute