Pluto Bioinformatics

GSE94631: Epigenome comparisons reveal linkage between gene expression and developmental remodeling of chromatin domain topology

Bulk RNA sequencing

We describe a new approach to ChIP-seq analysis in which conservation of nucleosome-scale H3K27me3 topology, rather than coverage, is quantified; RNA-seq results are related to the new ChIP-seq approach. SOURCE: Bruce,Hamilton,Howard (howard@helix.nih.gov) - Developmental Biology Group NIH/NICHD