Pluto Bioinformatics

GSE121999: Genome-wide expression analysis of EPCAM+ epithelial cells from 3-dimensional lung organoids harboring Hermansky-Pudlak Syndrome-associated mutations

Bulk RNA sequencing

Introduction of Hermansky-Pudlak Syndrome-associated mutations with CRISPR/Cas9 genome editing, allows for disease modeling in 3D cultures of hPSC-derived lung organoids. SOURCE: Hans-Willem Snoeck (hs2680@cumc.columbia.edu) - Columbia University Medical Center