Pluto Bioinformatics

GSE121142: Bcl9 and Pygo synergize downstream of Apc to effect intestinal neoplasia in mouse models recapitulating Familial Adenomatous Polyposis (RNA-Seq)

Bulk RNA sequencing

We assessed differential gene expression using RNAseq in intestinal adenomas between Apc loss-of-function (Apcmin) mice, or by Apc1322T mice encoding a partially-functional Apc truncation commonly found in colorectal carcinomas. SOURCE: Laurens,Moore,van Tienen MRC Laboratory of Molecular Biology