Pluto Bioinformatics

GSE97126: Constitutive Activation of HH-GLI Signaling in the Metanephric Mesenchyme causes Ureteropelvic Junction Obstruction during Mammalian Embryogenesis

Bulk RNA sequencing

This study explores the underlying pathogenic mechanisms of congenital intrinsic obstruction of the ureteropelvic junction. A hedgehog-dependent mechanism underlying mammalin intrinsic ureteropelvic obstruction is defined. SOURCE: Steve Potter (steve.potter@cchmc.org) - Cincinnati Children's Hospital Medical Center