Pluto Bioinformatics

GSE77179: Transcriptional changes in breast cancer cell lines associated with vascular mimicry

Bulk RNA sequencing

The goal of this study was to determine the transcriptional changes associated with breast cancer cells undergoing vascular mimicry in a 3D assay. Two breast cancer cell lines were plated on matrigel in the presence or absence of serum. MDA-MB-231 cells undergo vascular mimicry on matrigel in the absence of serum, MDA-MB-453 cells do not. SOURCE: Rosalie Sears (searsr@ohsu.edu) - Oregon Health & Science University