Pluto Bioinformatics

GSE90890: Osteoblast-specific deletion of Hrpt2/Cdc73 results in high bone mass and increased bone turnover

Bulk RNA sequencing

RNA-seq within OCN-Cre;Cdc73flox/flox osteoblasts showed that loss of Cdc73 led to a derepression of osteoblast-specific genes, specifically those for collagen and other bone matrix proteins. SOURCE: Casey,James,DroschaCell Signaling & Carcinogenesis Van Andel Institute