Pluto Bioinformatics

GSE132494: Dynamic Lineage Priming by ERK is Driven by Transcription Factor-Independent Enhancer Regulation [Med24_KO]

Bulk RNA sequencing

Extensive analysis if the means by which ERK affects transcription via enhancer regulation in mouse embryonic stem cells. This study combines analysis of mRNA, and nascent RNA dynamics and correlates this with changes in transcription factor, co-factor, and RNAPII binding and activity. SOURCE: Josh,M,Brickman (joshua.brickman@sund.ku.dk) - Brickman Copenhagen University