Pluto Bioinformatics
GSE116127: Transcriptomic analysis of the effect of trastuzumab in human iPSC-CMs
Bulk RNA sequencing
We used human iPSC-CMs generated from healthy individuals and performed RNA-sequencing after 7 days of trastuzumab treatment to examine the mechanism associated with contraction dysfunction in iPSC-CMs after trastuzumab treatment. Transcriptome analysis revealed the key role of an altered energy metabolism pathway for cardiomyocytes in the disease pathogenesis. SOURCE: Lei Tian (tianlei@stanford.edu) - Stanford's Postdoctoral Scholar programs