Pluto Bioinformatics

GSE123683: Transcriptome analysis upon C6orf203 silencing

Bulk RNA sequencing

In our studies we were searching for the new factors engaged in mitochondrial nucleic acids metabolism under stress conditions in humans. Quantitative proteomic approach revealed C6orf203 protein as a potential new factor engaged in response to perturbed mitochondrial gene expression. We showed that C6orf203 is a mitochondrial RNA binding protein which is able to rescue diminished mitochondrial transcription in stress conditions. SOURCE: Sylwia Czarnomska (s.czarnomska@gmail.com) - Laboratory of RNA Biology and Functional Genomics Institute of Biochemistry and Biophysics Polish Academy of Sciences