Pluto Bioinformatics

GSE115758: Loss of Sirt2 increase and prolongs a chemically induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mouse

Bulk RNA sequencing

Transcriptome analysis by RNA-seq in pancreas identified 529 differentially expressed genes between wild-type and Sirt2-deficient mice 2 days after injury and confirmed continuous inflammention and tissue regeneration, as well as delayed tissue reorganization. SOURCE: Nobuo Horikoshi (pica53@gmail.com) - Northwestern University