Pluto Bioinformatics

GSE109083: Transcriptomic analysis of microglia from 7 week Npc1 disease mouse model treated or not with 4000mg.kg-1 HPBCD

Bulk RNA sequencing

the study aims to describe the modifications occurring the microglia isolated from NPC1 disease mouse model using a transcriptomic and phenotypic approach. The analysis is also performed on animal treated with the reference drug HPBCD, currently under clinical trial in human. SOURCE: antony,cyril,cougnoux (antony.cougnoux@nih.gov) - stm nih