Pluto Bioinformatics

GSE140844: RNA Transcriptome of Tregs in Idiopathic Aplastic Anemia

Bulk RNA sequencing

Our report demonstrates that the dominant Treg population in AA are FasL resistant but do not respond to low concentration of IL-2, leading to immune dysregulation. And In vitro expanded AA Tregs are stable, functional and highly express p-BCL-2 with therapeutic potential in AA patients SOURCE: syed mian (syed.mian@kcl.ac.uk, syed.mian@crick.ac.uk) - King's College London