Pluto Bioinformatics

GSE101872: RNA Missplicing in Fuchs Endothelial Corneal Dystrophy

Bulk RNA sequencing

RNA-Seq splicing data from the corneal endothelia of FECD patients and controls reveal hundreds of differential alternative splicing events. These include events previously characterized in the context of myotonic dystrophy type 1 and epithelial-to-mesenchymal transition, as well as splicing changes in genes related to proposed mechanisms of FECD pathogenesis SOURCE: Keith,H,Baratz (Baratz.Keith@mayo.edu) - Mayo Clinic