Pluto Bioinformatics

GSE132383: Validation of small molecule activators and identification of altered signaling pathways underlying the age-related decline in proliferative capacity in human dermal progenitors

Bulk RNA sequencing

Intrinsic dysfunction of hair follicle dermal progenitors underlies phenotypic changes observed in aged dermis in rodents. The authors confirm similar age-related decline in function is present in adult human DPCs. RNA-Seq is utilized to identify further explanations for this functional decline in aged hDPCs. SOURCE: Matthew Workentine University of Calgary