Pluto Bioinformatics

GSE99296: -ketoglutarate orchestrates macrophage activation through metabolic and epigenetic reprogramming

Bulk RNA sequencing

We conducted gene expression analysis of naive and polarized macrophages from wild type C57BL6/J mice. In this project, we also compared how glutamine deprivation and production of alpha-ketoglutarate during LPS priming affects gene expression profiles in bone marrow-derived macrophages. SOURCE: Ping-Chih Ho (ping-chih.ho@unil.ch) - Immunometabolic regulation University of Lausanne