The aim of this experiment was to analyze differences in gene expression between potential osteoprogenitor populations in synovial compartment of non-immunized mice and mice with antigen-induced arthritis (AIA). We analyzed transcriptome of TER119CD31CD45CD51+CD200+CD105 cells from nonimmunized mice, TER119CD31CD45CD51+CD200+CD105 cells from mice with arthritis, and TER119CD31CD45CD51+CD200CD105+ from mice with arthritis. Comparison between nonimmunized and arthritic mice served to determine changes in TER119CD31CD45CD51+CD200+CD105population induced by arthritis. Comparison of TER119CD31CD45CD51+CD200+CD105 and TER119CD31CD45CD51+CD200CD105+ from mice with arthritis aimed to define transcriptomic differences between those two populations. SOURCE: Nina Lukač (nina.lukac@gmail.com) - Laboratory for Molecular Immunology University of Zagreb School of Medicine

Pluto Bioinformatics

GSE148130: Transcriptome analysis of synovial osteoprogenitor populations in mice with antigen-induced arthritis and non-immunized mice