Pluto Bioinformatics

GSE140739: Direct Phosphorylation and Stabilization of MYC by Aurora B Kinase Promote T Cell Leukemogenesis

Bulk RNA sequencing

Depletion of AURKB reduced the steady-state levels of MYC protein. We predicted that inactivation of AURKB would affect global MYC transcriptional program. To test this, RNA-Seq was performed using AURKB or control depleted CUTLL1 cells. SOURCE: jue jiang (juejiang@whu.edu.cn) - Wuhan University