Pluto Bioinformatics

GSE76837: Effects of in vivo expansion of mouse embryonic stem cells

Bulk RNA sequencing

Whe embryonic stem cells are in vitro expanded threir telomereres lengthen, in the absence of genetic manipulations, concomitant with the loss of heterochromatic marks. In order to analyze whether there would be changes in gene expression during in vitro expansion we performed RNA-seq and found no substantial differences in gene expression at passage 6 or 16. SOURCE: Elisa VarelaTelomeres and Telomerase Group CNIO