Pluto Bioinformatics

GSE102491: c-Maf-dependent transcripts in effector Tregs from Peyer's patches

Bulk RNA sequencing

We identify c-Maf as an essential factor regulating adoption of RORgamma t+ and T follicular regulatory phenotypes in effector Tregs. Differential expression analysis demonstrates reduced signatures of both ROR gamma t+ Tregs and T follicular regulatory cells following regulatory T cell-specific c-Maf deletion. SOURCE: Maria Ciofani (maria.ciofani@duke.edu) - Duke University Medical Center