Pluto Bioinformatics

GSE57602: RNAseq analysis of mouse lung transcriptome from allergic and non-allergic mice prior to and following lung Klebsiella pneumoniae infection

Bulk RNA sequencing

We have demonstrated that allergic airway inflammation (induced by an ovalbumin sensitization and aerosol challenge protocol) decreases lung bacterial burden following lung infection with Klebsiella pneumoniae. The goals of this study are to indentify novel targets that are expressed during allergic airway inflammation in this model that contribute to enhanced lung bacterial immunity. SOURCE: Daniel,E,Dulek (daniel.dulek@vanderbilt.edu) - Stokes Peebles, PI Vanderbilt University Medical Center