Pluto Bioinformatics

GSE112984: Characterization of myocardial B cells in nave hearts, acutely injured hearts and acutely injured hearts of mice treated with Pirfenidone

Bulk RNA sequencing

Myocardial CD19+CD11b+ and CD19+CD11b- cells were FACS sorted from transgenic mice expressing the Diphtheria Toxin (DT) receptor under the myocardial specific MLC2v promoter. Cells were sorted from hearts of mice not exposed to DT (nave hearts), from the hearts of animals treated with DT 4 days prior to the experiment (DTR) and from the hearts of mice exposed to DT and fed chow enriched with the anti-inflammatory/anti-fibrotic drug Pirfenidone (0.5% in powdered chow, PFD) SOURCE: Scot,J,Matkovich (smatkovich@gmail.com) - Washington University School of Medicine

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