Pluto Bioinformatics

GSE116286: Dynamic BAF chromatin remodeling complex subunit inclusion promotes temporally distinct gene expression programs in cardiogenesis [RNA-Seq II]

Bulk RNA sequencing

We performed differential mRNA analysis in WT and BRG1 KO cells during cardiac precursor and cardiomyocytes stages of directed differention of mouse ES cells to cardiac myocytes. We show that BRG1 activity is higher in cardiac precursor cells and severely reduced in cardiac myocytes SOURCE: Benoit Bruneau (benoit.bruneau@gladstone.ucsf.edu) - Gladstone Institute of Cardiovascular Disease