Pluto Bioinformatics

GSE81579: Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence.

Bulk RNA sequencing

RNA sequencing profiling of cumulus cells revealed that the follicles of older women have a compromised environment with hypoxic stress being the main contributor to age-related oocyte quality decay. SOURCE: Pasquale Patrizio (pasquale.patrizio@yale.edu) - Yale University