Pluto Bioinformatics

GSE137200: Pattern occupation of HDACs on chromatin determines PI3K/AKT inhibitor resistance in cancers [RNA-seq]

Bulk RNA sequencing

Blocking BRD4 or HDACs induces paradoxically similar gene expression, comparably attenuates PI3K/AKT inhibitor resistance in multiple cancer cells. SOURCE: Zhenqing Ye (iamyezhenqing@gmail.com) - Mayo Clinic