Pluto Bioinformatics
GSE111120: Deep transcriptomic analysis of human vascular cells identifies novel risk genes for common vascular diseases
Bulk RNA sequencing
Several genome-wide association studies have to date been carried out to identify genetic risk loci associated with vascular diseases. Many of the established common variants likely perturb the expression of disease-relevant genes within the vascular tissue itself. To identify such genes on a genome-wide level, we analyzed the transcriptome of human coronary artery smooth muscle and endothelial cells for Allele-Specific Expression (ASE). SOURCE: Sylvia,T,Nurnberg (sylvian@upenn.edu) - Rader University of Pennsylvania