Pluto Bioinformatics

GSE83145: RNA profiling of testis from wild-type and tamoxifen-induced NIPP1 knockout mice

Bulk RNA sequencing

This study aimed to explore the role of NIPP1 in adult germline cell proliferation and differentiation, using a ubiquitous inducible NIPP1 knockout (TKO) mouse model. To gain unbiased insight into the molecular mechanism that underly the sertoli-only phenotype in TKO, we performed a comparative RNA sequencing profiling of control and TKO, in which NIPP1 was tamoxifin-induced depleted. SOURCE: Wouter Van Delm ( - Flanders Institute for Biotechnology (VIB)

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