Pluto Bioinformatics

GSE57415: Molecular architecture of transcription factor hotspots in early adipogenesis

Bulk RNA sequencing

Here, we have used digital genomic footprinting to precisely define protein localization for several adipogenic transcription factors at a genome-wide level. In combination with ChIP-seq data, these analyses reveal novel molecular insight into the organization of transcription factors at hotpot regions, which provides a new framework for understanding transcription factor cooperativity on chromatin. SOURCE: Susanne Mandrup (s.mandrup@bmb.sdu.dk) - University of Southern Denmark