Pluto Bioinformatics

GSE101558: Genome expression analysis of Lung Progenitors matured in the presence of constitutively active or pharmacologically inhibited Glycogen Synthase Kinase 3

Bulk RNA sequencing

In 3D cultures of hPSC-derived lung progenitors withdrawal of the GSK3 inhibitor, CHIR99021, induces multilineage maturation, including of proximal cells, type I alveolar epithelial cells and morphologically mature type II cells. SOURCE: Hans-Willem Snoeck (hs2680@cumc.columbia.edu) - Columbia University Medical Center