Nrn1-/- and Nrn1+/- Thy1.1+ OTII cells were cotransferred with wt Treg cell into TCRa-/- hosts and subjected to soluble OVA peptide i.v. treatment for anergy induction on day 1, 4, and 7 post transfer. Nrn1-/- and Nrn1+/- Thy1.1+ OTII cells were recoverred by cell sorting 13 days after cell transferand subjected to RNA-Sequencing analysis SOURCE: Drew Pardoll (dpardol1@jhmi.edu) - Pardoll Johns Hopkins Medical Institute

Pluto Bioinformatics

GSE121908: RNA-sequencing on Nrn1-/- and Nrn1+/- OTII cells recovered from OVA-peptide induced anergy TCRa-/- host mice