Pluto Bioinformatics

GSE128343: A large panel of isogenic APP and PSEN1 mutant human iPSC neurons reveals shared endosomal abnormalities mediated by APP b-CTFs, not Ab [RNA-seq]

Bulk RNA sequencing

Human iPS cells with different mutations linked to Alzheimer's Disease were differentiated into neurons and subjected to RNAseq to identify Alzheimer's Disease associated changes SOURCE: Claudia Scheckel (claudia.scheckel@rockefeller.edu) - The Rockefeller University