Pluto Bioinformatics

GSE127197: Attenuation of progesterone driven mammary stem cells population by telapristone acetate

Bulk RNA sequencing

ovariectomized mice treated with E2+Progesterone, E2+Progesterone+TPA, E2+Progesterone+RU486 and sham for 14 days, followed by isolation of luminal mature, luminal progenitor and mammary stem cells through FACS and RNASeq performed for each cell lineage population. TPA and RU486 treated mice show significant decline in mammary stem cell pool pulation comapared to EP treated mice SOURCE: Seema,Ahsan,Khan (s-khan2@northwestern.edu) - Northwestern University